Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs). Objective: To review published RCM terms for NMLs and identify likely synonymous terms. Methods: We conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus–like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates. Results: The inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5% reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7%) versus 78 (74.2%) for BCC; 60 (64.5%) versus 33 (34.5%) for SCC, and 15 (45.4%) versus 18 (54.5%) for SK/SL/LPLK, respectively. Limitations: Articles that were not peer reviewed were excluded. Conclusion: Systematic review of published RCM terms provides the basis for future NMLs terminology consensus.

Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions: A systematic review / Navarrete-Dechent, C.; Derosa, A. P.; Longo, C.; Liopyris, K.; Oliviero, M.; Rabinovitz, H.; Marghoob, A. A.; Halpern, A. C.; Pellacani, G.; Scope, A.; Jain, M.. - In: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. - ISSN 0190-9622. - 80:5(2019), pp. 1414-1427.e3. [10.1016/j.jaad.2018.12.007]

Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions: A systematic review

Pellacani G.;
2019

Abstract

Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs). Objective: To review published RCM terms for NMLs and identify likely synonymous terms. Methods: We conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus–like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates. Results: The inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5% reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7%) versus 78 (74.2%) for BCC; 60 (64.5%) versus 33 (34.5%) for SCC, and 15 (45.4%) versus 18 (54.5%) for SK/SL/LPLK, respectively. Limitations: Articles that were not peer reviewed were excluded. Conclusion: Systematic review of published RCM terms provides the basis for future NMLs terminology consensus.
2019
actinic keratosis; basal cell carcinoma; diagnosis; lichen planus-like keratosis; melanoma; nonmelanoma skin cancer; reflectance confocal microscopy; seborrheic keratosis; squamous cell carcinoma; Carcinoma; Basal Cell; Carcinoma; Squamous Cell; Humans; Keratosis; Seborrheic; Lentigo; Microscopy; Confocal; Skin Neoplasms; Terminology as Topic
01 Pubblicazione su rivista::01a Articolo in rivista
Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions: A systematic review / Navarrete-Dechent, C.; Derosa, A. P.; Longo, C.; Liopyris, K.; Oliviero, M.; Rabinovitz, H.; Marghoob, A. A.; Halpern, A. C.; Pellacani, G.; Scope, A.; Jain, M.. - In: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. - ISSN 0190-9622. - 80:5(2019), pp. 1414-1427.e3. [10.1016/j.jaad.2018.12.007]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1482875
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 10
  • Scopus 33
  • ???jsp.display-item.citation.isi??? 25
social impact